Navigating the Deubiquitinating Proteome with a CompPASS

نویسنده

  • Peter K. Jackson
چکیده

Deubiquitinating enzymes (DUBs) act on ubiquitinated substrates to regulate their modification and stability. In this issue, Sowa et al. (2009) present a comprehensive proteomic analysis of DUB interacting proteins in humans and a new quantitative scoring system for hits (CompPASS), providing a resource that links DUBs to biological pathways.

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عنوان ژورنال:
  • Cell

دوره 138  شماره 

صفحات  -

تاریخ انتشار 2009